Figure 7. A reconstructed model for the morphogenetic network of A. niger based on the transcriptomic fingerprints determined for the apical branching mutant ramosa-1 [25], the apical branching mutant ΔracA (this work) and the apolar growing mutant PglaA-RacAG18V (this work).
The model also rests on cell biological and phenotypic data obtained for all three strains (this work and [25]) as well as on literature data for conserved mechanisms from yeast to humans (see discussion for references). Indicated are signalling and metabolic processes, which showed transcriptional responses in all three strains, some deduced key players and the hypothetical connection of these processes.