Figure 7. Effects of co-injection of LTM-inducing drugs and LTM-inhibiting drugs on visual LTM induction.

At 20 min prior to 4-trial visual conditioning, four groups of animals were each co-injected with 3 μl of saline containing NOR4 (10 μM) and L-NAME (400 μM), NOR4 (10 μM) and DDA (1 mM), 8-br-cAMP (200 μM) and L-NAME (400 μM), or 8-br-cAMP (200 µM) and DDA (1 mM). Relative preference between the rewarded pattern and control pattern was tested before and at 1 day after conditioning. The PIs for the rewarded pattern before (white bars) and after (grey bars) training are shown as box plots, and the results of statistical comparison are indicated (** p<0.01, * p<0.05, NS p>0.05, WCX test).