Table 3. Relative Saa3 mRNA levels in lung and liver tissue after pulmonary deposition of particles.
Particle | Study | Exposure set-up | Reference | Liver | Lung | ||
Control | Exposed | Control | Exposed | ||||
NanoCB | 3 | Inhalation: 4×1.5 h×20 mg/m3 | [32] | 25±37 | 19±7.8 | 25±30 | 111±63* |
DEP | 3 | Inhalation: 4×1.5 h×20 mg/m3 | [32] | 25±37 | 38±16 | 25±30 | 435±662* |
Boiler dust | 6 | Intratracheal instillation: 4×54 µg | [31] | ND† | ND† | 563±540 | 3337±3006* |
Straw dust | 6 | Intratracheal instillation: 4×54 µg | [31] | ND† | ND† | 563±540 | 6389‡5520* |
Saa3 mRNA levels were normalised to 18S and multiplied by 107. Mean±SD is shown. * p<0.001 compared to controls. † Not determined.