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. 2013 Jul 24;8(7):e69020. doi: 10.1371/journal.pone.0069020

Table 4. Relative Saa3 mRNA levels in lung and liver tissue after pulmonary deposition of particles by inhalation.

Particle Study Exposure set-up Reference 4–5 days after exposure ∼4weeks after exposure
Liver Lung Liver Lung
Control Exposed Control Exposed Control Exposed Control Exposed
NanoTiO2 4 11××1 h×42 mg/m3 [23] 201±336 70±51 24±12 570±418† 605±369 486±283 1576±4329 3337±3808‡
(330±376)§ (2384±1722)§
NanoCB 5 11×1 h×42 mg/m3 [22] 52±27 116±48 15±8 43±16† 44±33 79±47* 15±6 43±16†

Saa3 mRNA levels were normalised to 18S and multiplied by 107. Mean±SD is shown. * p<0.05, p<0.01, p<0.001, §One outlier has been removed in each group.