Table 4.

Grey matter atrophy in patients with Alzheimer’s disease and semantic variant PPA relative to healthy seniors

Anatomical locus (Brodmann area)	MNI coordinates			Z-score	Cluster size (voxels)
	x	y	z
Alzheimer’s disease < healthy seniors
L fusiform gyrus (20)	−44	−28	−22	7.52	5935
L middle temporal gyrus (21)	−50	−8	−18	5.20	198
L superior temporal gyrus (38)	−52	14	−22	4.01	64
L inferior parietal lobule (40)	−40	−16	20	4.90	448
L inferior parietal lobule (40)	−46	−24	32	3.98	52
L inferior parietal lobule (40)	−42	−36	22	4.53	97
L angular gyrus (39)	−40	−72	28	4.59	52
L precuneus (7)	−10	−62	40	4.79	60
L precuneus (31)	−12	−48	34	4.66	95
L inferior frontal gyrus (45)	−38	30	6	4.91	272
L inferior frontal gyrus (11)	−28	38	−14	4.70	101
L middle frontal gyrus (9)	−32	12	34	4.71	255
L middle frontal gyrus (46)	−50	30	26	4.30	91
L medial frontal gyrus (9)	−10	48	16	4.72	70
L subcallosal gyrus (25)	−10	20	−18	5.01	273
R parahippocampal gyrus (36)	26	−34	−16	5.11	232
R fusiform gyrus (36)	40	−28	−26	4.32	66
R parahippocampal gyrus (30)	12	−50	2	3.93	158
R superior occipital gyrus (19)	44	−76	32	3.94	95
R anterior cingulate gyrus (32)	14	38	22	4.55	71
Semantic variant PPA < healthy seniors
L inferior temporal gyrus (20)	−50	0	−32	7.41	570
L fusiform gyrus (20)	−46	−30	−24	6.14	524
R fusiform gyrus (20)	40	−20	−30	5.49	63

L = left; R = right.