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. Author manuscript; available in PMC: 2013 Jul 24.

Published in final edited form as: Mol Carcinog. 2008 Feb;47(2):88–99. doi: 10.1002/mc.20365

Table 5.

Association Between Smoking Status and p53 Mutations

	# mutations/#		Crude OR	Adjusted OR^a
Smoking status	tumors	%	(95% CI)	(95% CI)
Any p53 mutation
Never	15/185	8.1	Reference	Reference
Former	11/85	12.9	1.69 (0.74–3.84)	2.14 (0.82–5.57)
Current	6/39	15.4	2.06 (0.75–5.70)	1.09 (0.35–3.24)
Transitions
Never	10/185	5.4	Reference	Reference
Former	6/85	7.1	1.33 (0.47–3.79)	1.90 (0.59–6.13)
Current	2/39	5.1	0.95 (0.20–4.50)	0.40 (0.07–2.21)
Transversions
Never	5/185	2.7	Reference	Reference
Former	3/85	3.5	1.32 (0.31–5.64)	1.01 (0.17–5.87)
Current	3/39	7.7	3.00 (0.69–13.12)	2.34 (0.46–11.85)

^a

Adjusted for age, age of menarche, BMI, and tumor stage.