Table 3.
Histologic changes associated with SARS-CoV
Tissue | Diagnosis | Group | 1 | 2 | 3 | 4 | 5 | 6 | Control | Control |
---|---|---|---|---|---|---|---|---|---|---|
Sacrifice day | 2 | 2 | 5 | 5 | 19 | 19 | 19 | 19 | ||
Virus | + | + | + | + | + | + | − | − | ||
CP-D | − | + | − | + | − | + | − | + | ||
Severity | ||||||||||
Heart | Number examined | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
No significant lesions | 2 | 2 | 2 | 2 | 2 | 0 | 2 | 2 | ||
Inflammation, subacute | Minimal | 2 | ||||||||
Kidney | Number examined | 0 | 0 | 0 | 0 | 2 | 2 | 2 | 2 | |
No significant lesions | 2 | 0 | 2 | 2 | ||||||
Dilation, tubular | Mild | 1 | ||||||||
Degeneration/necrosis, tubular | Mild | 1 | ||||||||
Lung | Number examined | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
No significant lesions | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 2 | ||
Inflammation, subacute | Minimal | 2 | 1 | 1 | 2 | |||||
Pneumonia, bronchointerstitial | Mild | 1 | ||||||||
Moderate | 2 | 1 | 1 | |||||||
Nasal turbinate | Number examined | 2 | 2 | 2 | 2 | 2 | 2 | 2 | 2 | |
No significant lesions | 0 | 0 | 0 | 0 | 2 | 0 | 2 | 2 | ||
Exudate, fibrinopurulent | Minimal | 1 | ||||||||
Mild | 1 | 1 | 1 | 1 | ||||||
Moderate | 2 | 1 | 1 | 1 |