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MMP-9 expression at 72 hrs after ischemia. (A) Representative photomicrographs showing immunoreactivity for MMP-9 within the ischemic area in WT and CD47 KO brains. MMP-9 appeared co-localized with the endothelial marker CD31. Scale bar: 50 μm. (B) Quantitative data showing a significant reduction of MMP-9 immunostaining image density in CD47 KO compared to WT brains, *p<0.05.
