Figure 5.
Surface representation of C. jejuni PglE binding pocket. The crystal structure of the homologous aminotransferase PseC bound to the PMP-UDP-l-AltNAc external aldimine (2FNU) was utilized to define the active site. Following alignment with the PLP-bound PglE crystal structure (1O61), amino acids within 5 Å of the external aldimine were identified as binding-pocket residues.