Table 4. Endpoints in 13 randomized trials comparing CAS and CEA*1.
Endpoints | Number of patients*2 | Number of trials*2 | CAS | CEA | Absolute risk difference (CAS versus CEA) | Pooled odds ratio(95% confidence interval) |
---|---|---|---|---|---|---|
Any periprocedural stroke or death | 7390 | 12 | 6.7% | 4.4% | + 2.3% | 1.54 (1.25–1.89) |
Any periprocedural stroke | 7171 | 11 | 6.0% | 3.9% | + 2.1% | 1.53 (1.23–1.91) |
Any stroke (mean follow-up 2.7 years) | 5359 | 9 | 10.8% | 8.2% | + 2.6% | 1.37 (1.13–1.65) |
Periprocedural myocardial infarction | 5952 | 9 | 0.8% | 1.7% | – 0.9% | 0.48 (0.29–0.78) |
Periprocedural cranial nerve dysfunction | 6062 | 11 | 0.3% | 5.4% | – 5.1% | 0.09 (0.05–0.16) |
*1Modified from (30)
*2Number of patients and trials in which the endpoint in question was used CAS, carotid stenting; CEA, carotid endarterectomy