Table 7.
Cytokines alleles and genotypes frequencies in HPV patients and controls.
| Cytokine alleles and genotypes | HPV patients N = 79 n (f%) |
Controls N = 101 n (f%) |
Cytokine alleles and genotypes | HPV patients N = 79 n (f%) |
Controls N = 100 n (f%) |
|---|---|---|---|---|---|
| TNF −308 | IL10 −1082 | ||||
| G | 139 (88.0) | 174 (86.1) | G | 50 (32.1) | 72 (36) |
| A | 19 (12.0) | 28 (13.9) | A | 106 (68) | 128 (64) |
| G/G | 62 (78.5) | 73 (72.3) | G/G | 9 (11.5) | 12 (12) |
| G/A | 15 (19.0) | 28 (27.7) | G/A | 32 (41.0) | 48 (48) |
| A/A | 2 (2.5) | 0 (0) | A/A | 37 (47.4) | 40 (40) |
|
| |||||
| INFG +874 | IL10 −819 | ||||
| T | 69 (44.2) | 88 (44.9) | C | 98 (62.8) | 129 (64.5) |
| A | 87 (55.8) | 108 (55.1) | T | 58 (37.2) | 71 (35.5) |
| T/T | 19 (24.4) | 19 (19.4) | C/C | 31 (39.8) | 42 (42) |
| T/A | 31 (39.7) | 50 (51.0) | C/T | 36 (46.2) | 45 (45) |
| A/A | 28 (35.9) | 29 (29.6) | T/T | 11 (14.1) | 13 (13) |
|
| |||||
| IL6 −174 | IL10 −592 | ||||
| G | 116 (73.4) | 132 (65.4) | C | 98 (62.8) | 129 (64.5) |
| C | 42 (26.6) | 70 (34.7) | A | 58 (37.2) | 71 (35.5) |
| G/G | 44 (55.7) | 45 (44.6) | C/C | 31 (39.8) | 42 (42) |
| G/C | 28 (35.4) | 42 (41.6) | C/A | 36 (46.2) | 45 (45) |
| C/C | 7 (8.9) | 14 (13.9) | A/A | 11 (14.1) | 13 (13) |
|
| |||||
| TGFB1 +869 | TGFB1 +915 | ||||
| T | 89 (56.3) | 108 (54) | G | 141 (89.2) | 190 (95) |
| C | 69 (43.7) | 92 (46) | C | 17 (10.7) | 10 (5) |
| T/T | 26 (32.9) | 25 (25) | G/G | 63 (79.8) | 90 (90) |
| T/C | 37 (46.8) | 58 (58) | G/C | 15 (19.0) | 10 (10) |
| C/C | 16 (20.3) | 17 (17) | C/C | 1 (1.3) | 0 (0) |
n: number of observed alleles and genotypes; f%: allele and genotype frequencies.
Difference was not observed between both groups (P ≥ 0.05).