Table 5.
Adverse events in patients reported in the two groups during treatment.
| Variable | Treatment group Number of patients (%) (n = 200) |
Control group Number of patients (%) (n = 100) |
χ 2 (Chi-square test) | P values |
|---|---|---|---|---|
| Abdominal pain | 9 (4.5) | 3 (3) | 0.3906 | 0.5320 |
| Abdominal distension | 15 (7.5) | 2 (2) | 3.7726 | 0.0521 |
| Diarrhea | 14 (7) | 3 (3) | 1.9954 | 0.1578 |
| Nausea | 5 (2.5) | 2 (2) | 0.0000△ | 1.0000 |
| Increased appetite | 34 (17) | 1 (1) | 16.5606 | 0.0000 |
| Appetite decreases | 5 (2.5) | 4 (4) | 0.1289△ | 0.7196 |
| Feel thirsty | 4 (2) | 3 (3) | 0.0183△ | 0.8924 |
| Stomach disturbances | 19 (9.5) | 5 (5) | 1.8342 | 0.1756 |
| Constipation | 4 (2) | 3 (3) | 0.0183△ | 0.8924 |
| Malaise | 5 (2.5) | 2 (2) | 0.0000△ | 1.0000 |
| Insomnia | 3 (1.5) | 1 (1) | 0.0000△ | 1.0000 |
| Headache | 3 (1.5) | 2 (2) | 0.0000△ | 1.0000 |
| Dizziness | 5 (2.5) | 1 (1) | 0.1913△ | 0.6618 |
| Fatigue | 3 (1.5) | 2 (2) | 0.0000△ | 1.0000 |
| Chest tightness | 4 (2) | 3 (3) | 0.0183△ | 0.8924 |
| URTI syndromes※ | 3 (1.5) | 3 (3) | 0.1913△ | 0.6618 |
| Mouth ulceration | 3 (1.5) | 2 (2) | 0.0000△ | 1.0000 |
| Rash | 5 (2.5) | 0 (0) | 1.2458△ | 0.2644 |
| Dysuria | 2 (1) | 0 (0) | 0.0629△ | 0.8019 |
| Urethral burning pain | 2 (1) | 0 (0) | 0.0629△ | 0.8019 |
| Increased serum ALT※ | 3 (1.5) | 0 (0) | 0.3788△ | 0.5383 |
※URTI: upper respiratory tract infection; increased serum ALT defined as >40 U/L.
△Correction.