TABLE 2.

Chronic Symptoms and Spirometry Results

Patient	Chronic symptoms1	FEV1% predicted	FEV1/FVC	% increase in FEV1 after bronchodilator	Medications used before challenge2	Parental history of asthma	Allergy to aeroallergens	TLC, % predicted	RV/TLC, %
Patients with a positive challenge
1	1	783	99	2%	ICS	No	No	NT	NT
2	1, 2, 3, 4	99	84	11%	ICS, LTRA	No	Yes	93	27
3	1, 3	91	95	NT4	None	Yes	Yes	NT	NT
4	1, 3, 4	82	82	4%	ICS, LABA	No	NT	97	23
5	1, 3	83	93	1%	ICS	No	Yes	84	34
6	1, 2, 4	94	93	NT	None	No	Yes	102	355
7	1, 2, 3	94	83	6%	ICS, LABA	No	Yes	NT	NT
8	1, 2	88	78	4%	None	No	Yes	109	25
9	None	91	86	2%	ICS, LABA	Yes	Yes	92	30
10	1	643	713	9%	None	No	Yes	96	25
11	2, 3	115	87	1%	ICS, LABA	No	Yes	98	22
12	1, 3	773	91	0%	ICS, LABA	No	NT	88	32
13	1, 3	106	84	1%	ICS, LABA	Yes	Yes	NT	NT
14	1, 2, 3, 4	96	87	2%	ICS, LABA	Yes	No	NT	NT
Patients with a negative challenge
15	None	121	85	6%	None	No	Yes	113	34
16	None	83	91	5%	None	No	NT	112	19
17	1, 3	97	88	2%	None	No	NT	91	375
18	3, 4	88	92	3%	None	Yes	Yes	100	355
19	2, 3	85	97	2%	None	No	Yes	94	365
20	1, 3, 4	88	83	–2%	ICS, LABA	No	No	89	33
21	1, 3	783	91	2%	ICS	No	No	100	27

¹(1) Wheeze; (2) cough with exercise; (3) shortness of breath with exercise; (4) night time awakening from cough or wheeze.

²ICS, inhaled corticosteroid; LTRA, leukotriene receptor antagonist; LABA, long acting bronchodilator agent.

³Below normal range (29).

⁴Not tested.

⁵Above normal range (24).