Table 1.
Biochemical and epidemiological data according the development to acute kidney injury (AKI) (n = 303) and healthy individuals (control) (n = 244)
| AKI | ||||
|---|---|---|---|---|
| Yes (n = 139) | No (n = 164) | Control (n = 244) | P | |
| Age (years) | 67 ± 17 | 65 ± 18 | 60 ± 10 | 0·67 |
| Gender (male) | 91 (66%) | 97 (60%) | 154 (61%) | 0·26 |
| APACHE II score | 20 ± 7 | 17 ± 6 | – | 0·001 |
| MDRD | 70 ± 51 | 100 ± 49 | 81 ± 13 | 0·001 |
| Creatinine (mg/dl) | 1·07 ± 1·20 | 0·40 ± 0·70 | 1·00 ± 0·2 | 0·0001 |
| Albumin (mg/dl) | 3·06 ± 0·25 | 3·24 ± 0·54 | 4·5 ± 0·3 | 0·22 |
| CRP (mg/dl) | 7·89 ± 8·61 | 7·20 ± 8·47 | 0·56 ± 0·69 | 0·48 |
| Vasoactive drug | 24 (17%) | 6 (4%) | – | 0·0001 |
| Mechanical ventilation | 29 (21%) | 11 (7%) | – | 0·0001 |
| Sepsis | 44 (32%) | 35 (21%) | – | 0·04 |
| Coronary artery disease/heart failure | 26 (19%) | 31 (19%) | 24 (10%) | 0·96 |
| Stroke | 7 (5%) | 13 (8%) | – | 0·31 |
| Hypertension | 54 (39%) | 66 (40%) | 73 (29%) | 0·80 |
| Diabetes mellitus | 25 (18%) | 31 (19%) | 32 (13%) | 0·83 |
| Chronic kidney disease | 1 (0·01%) | 3 (0·02%) | – | 0·60 |
| Mortality rate (%) | 12 (9%) | 7 (4%) | – | 0·12 |
Comparison between AKI and no-AKI: Student's t- and χ2 tests. MDRD: modification of diet in renal disease; APACHE: acute physiology and chronic health evaluation; CRP: C-reactive protein.