Table 6.
Frequency of genotypes of tumour necrosis factor (TNF)-α, interleukin (IL)-6 and IL-10 polymorphisms in the acute kidney injury (AKI) group according mechanical ventilation, vasoactive drug and sepsis after intensive care unit (ICU) admission
| Mechanical ventilation* | Vasoactive drug* | Sepsis* | ||||
|---|---|---|---|---|---|---|
| Polymorphism | No | Yes | No | Yes | No | Yes |
| TNF-α | ||||||
| AA | 3 (3%) | 0 (0%) | 3 (3%) | 0 (0%) | 3 (3%) | 0 (0%) |
| GA | 49 (44%) | 11 (38%) | 47 (41%) | 12 (50%) | 43 (45%) | 17 (39%) |
| GG | 58 (53%) | 18 (62%) | 64 (56%) | 12 (50%) | 49 (52%) | 27 (61%) |
| IL-6 | ||||||
| CC | 24 (22%) | 8 (28%) | 25 (22%) | 7 (30%) | 22 (23%) | 10 (23%) |
| GC | 29 (26%) | 4 (14%) | 28 (25%) | 4 (17%) | 18 (19%) | 15 (34%) |
| GG | 45 (41%) | 15 (52%) | 48 (42%) | 12 (50%) | 43 (45%) | 17 (39%) |
| IL-10 | ||||||
| AA | 32 (29%) | 11 (33%) | 34 (30%) | 9 (38%) | 29 (31%) | 14 (32%) |
| GA | 65 (59%) | 15 (52%) | 66 (58%) | 13 (44%) | 56 (59%) | 24 (55%) |
| GG | 10 (9%) | 3 (10%) | 11 (10%) | 2 (8%) | 7 (8%) | 6 (14%) |
*
No statistical differences between groups or genotype/phenotype; P > 0·05.