Table 8.
Relationship between tumour necrosis factor (TNF)-α plus low interleukin (IL)-10 producer and risk of acute kidney injury (AKI) and/or death and renal replacement therapy (RRT) and/or death
| Outcomes | OR | 95% CI | P |
|---|---|---|---|
| AKI and/or death | |||
| Unadjusted | 2·37 | 1·16–4·84 | 0·02 |
| Adjusted for age (years) | 2·34 | 1·14–4·80 | 0·02 |
| Adjusted for age and gender (male) | 2·40 | 1·16–4·95 | 0·02 |
| Adjusted for age, gender and ethnicity (Caucasian) | 2·83 | 1·32–6·07 | 0·007 |
| Adjusted for age, gender, ethnicity and APACHE score II | 2·87 | 1·29–6·38 | 0·009 |
| Adjusted for age, gender, ethnicity, APACHE II score and sepsis | 3·05 | 1·36–6·85 | 0·007 |
| Adjusted for age, gender, ethnicity, APACHE II score, sepsis and albumin | 3·05 | 1·35–6·87 | 0·007 |
| Adjusted for age, gender, ethnicity, APACHE II score, sepsis, albumin and CRP | 3·05 | 1·35–6·91 | 0·007 |
| RRT and/or death | |||
| Unadjusted | 3·82 | 1·19–12·23 | 0·02 |
| Adjusted for age (years) | 3·93 | 1·22–12·68 | 0·02 |
| Adjusted for age and gender (male) | 3·97 | 1·23–12·80 | 0·02 |
| Adjusted for age, gender and ethnicity (Caucasian) | 4·61 | 1·25–16·95 | 0·02 |
| Adjusted for age, gender, ethnicity and APACHE II score | 4·76 | 1·22–18·52 | 0·02 |
| Adjusted for age, gender, ethnicity, APACHE II score and sepsis | 7·15 | 1·66–30·67 | 0·008 |
| Adjusted for age, gender, ethnicity, APACHE II score, sepsis and albumin | 6·65 | 1·51–29·30 | 0·01 |
| Adjusted for age, gender, ethnicity, APACHE II score, sepsis, albumin and CRP | 6·74 | 1·52–29·76 | 0·01 |
APACHE: acute physiology and chronic health evaluation; CRP: C-reactive protein; OR: odds ratio; CI: confidence interval.