Table 2. CMA results according to the indication for prenatal diagnosis.

		No. Samples with a pathogenic CNV (%)
Indication	No. of Samples analyzed (%)	Detected by conventional karyotyping	Not detected by conventional karyotyping	Total	CMA detection rate (%)
Abnormal ultrasound findings	95 (3.2)	20 (76.9)	6 (23.1)	26 (27.4)	6.3
Advanced maternal age	1118 (37.3)	28 (82.4)	6 (17.6)	34 (3.0)	0.5
Parental anxiety	1675 (55.8)	17 (60.7)	11 (39.3)	28 (1.7)	0.7
Abnormal fetal karyotype	25 (0.8)	3 (75.0)	1 (25.0)	4 (16.0)	4.0
Abnormal maternal serum screening test	29 (1.0)	3 (100.0)	0 (0.0)	3 (10.3)	0.0
Family history of a genetic condition	25 (0.8)	0 (0.0)	0 (0.0)	0 (0.0)	0.0
Cell culture failure	33 (1.1)	0 (0.0)	0 (0.0)	0 (0.0)	0.0
High risk pregnancies (abnormal ultrasound findings+abnormal fetal karyotype)	120 (4.0)	23 (76.7)	7 (23.3)	30 (25.0)	5.8
Low risk pregnancies (advanced maternal age+ parental anxiety+abnormal maternal serum screening test+family history of a genetic condition+cell culture failure)	2880 (96.0)	48 (73.8)	17 (26.2)	65 (2.3)	0.6
Total	3000	71 (74.7)	24 (25.3)	95 (3.2)	0.8