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In vitro release curves of RIF-NPs using the modified cylinder method. (a) RIF-Gel-NPs with drug loading of 21.6% w/w in the presence and absence of trypsin; (b) RIF-Gel-NPs with drug loading of 56.7% w/w in the presence and absence of trypsin; (c) RIF-Gel-NPs with different loadings in PBS with pH 7.4; (d) RIF-PBCA-NPs in buffers with different pH values. Data shown is the mean ± S.D. (n = 3).
