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. Author manuscript; available in PMC: 2014 Mar 25.

Published in final edited form as: Angew Chem Int Ed Engl. 2013 Feb 19;52(13):3703–3708. doi: 10.1002/anie.201208292

(a) SDS-PAGE analysis of TRAIL-ELP reactions run in parallel with triglycine (Gly₃) or triglycine-modified camptothecin (Gly₃-CPT). Shown left to right for each reaction are the raw product, centrifugation pellet, and centrifugation supernatant. (b) Cell death in MDA-MB-231 cells treated with TRAIL (), Gly₃-CPT (), TRAIL-CPT conjugate (), or a mixture of Gly₃-CPT and TRAIL at a 0.8:1 molar ratio. (). For combination treatments, the TRAIL concentration is indicated. The viable cell number is reported relative to an untreated group. Error bars indicate standard deviations.

Inline graphic — (a) SDS-PAGE analysis of TRAIL-ELP reactions run in parallel with triglycine (Gly₃) or triglycine-modified camptothecin (Gly₃-CPT). Shown left to right for each reaction are the raw product, centrifugation pellet, and centrifugation supernatant. (b) Cell death in MDA-MB-231 cells treated with TRAIL (), Gly₃-CPT (), TRAIL-CPT conjugate (), or a mixture of Gly₃-CPT and TRAIL at a 0.8:1 molar ratio. (). For combination treatments, the TRAIL concentration is indicated. The viable cell number is reported relative to an untreated group. Error bars indicate standard deviations.