Table 1.
Pooled Sample (N = 198) |
AIM Study (n = 162) |
ONS Study (n = 36) |
|||||
---|---|---|---|---|---|---|---|
Characteristic | M | (SD) | M | (SD) | M | (SD) | p |
Age (years) | 59.1 | (7.5) | 60.6 | (6.1) | 52.4 | (9.5) | .0001 |
Education (years) | 15.0 | (2.9) | 15.1 | (3.0) | 14.8 | (2.7) | .64 |
Adherence | 88.7 | (1.6) | 87.2 | (24.6) | 95.4 | (8.9) | .21 |
Depression (BDI total score) | 6.0 | (5.7) | 5.8 | (5.6) | 6.7 | (6.0) | .37 |
Fatigue (POMS fatigue score) | 6.1 | (6.1) | 6.2 | (6.1) | 5.7 | (6.0) | .70 |
Anxiety (POMS anxiety score) | 6.7 | (4.6) | 6.8 | (4.5) | 6.5 | (5.0) | .38 |
n | (%) | n | (%) | n | (%) | ||
Marital status | .80 | ||||||
Never married | 20 | (10.1) | 18 | (11.1) | 2 | (5.6) | |
Currently married | 136 | (68.7) | 109 | (67.3) | 27 | (75.0) | |
Widowed | 16 | (8.1) | 13 | (8.0) | 3 | (8.3) | |
Separated | 2 | (1.0) | 2 | (1.2) | 1 | (0.0) | |
Divorced | 24 | (12.1) | 20 | (12.3) | 4 | (11.1) | |
Employed | .55 | ||||||
Yes | 138 | (69.7) | 111 | (68.5) | 27 | (75.0) | |
No | 60 | (30.3) | 51 | (31.5) | 9 | (25.0) | |
Ethnicity | .08 | ||||||
White | 194 | (98.0) | 159 | (98.1) | 35 | (97.2) | |
African American | 3 | (1.5) | 3 | (1.9) | 0 | (0.0) | |
Multi-racial | 1 | (0.5) | 0 | (0.0) | 1 | (2.8) | |
Latino | 2 | (1.0) | 1 | (0.6) | 1 | (2.8) | |
Primary occupation | .06 | ||||||
1. Higher executivea | 50 | (26.2) | 40 | (20.9) | 10 | (5.2) | |
2. Administrativeb | 64 | (33.5) | 51 | (26.7) | 13 | (6.8) | |
3. Skilled/nonskilledc | 24 | (12.6) | 20 | (10.5) | 4 | (2.1) | |
4. Homemaker/otherd | 53 | (27.7) | 51 | (26.7) | 2 | (1.0) | |
Menopausal status | .0001 | ||||||
Premenopausal | 16 | (8.1) | 0 | (0.0) | 16 | (44.4) | |
Postmenopausal | 182 | (91.9) | 162 | (100.0) | 20 | (55.6) | |
MEMS-monitored medication | .0001 | ||||||
Anastrozole | 69 | (85.4) | 62 | (100.0) | 7 | (19.4) | |
Letrozole | 9 | (3.5) | 0 | (0.0) | 7 | (19.4) | |
Examestane | 2 | (1.0) | 0 | (0.0) | 2 | (5.6) | |
Tamoxifen | 19 | (9.6) | 0 | (0.0) | 19 | (52.8) | |
Multiple AIs | 1 | (0.5) | 0 | (0.0) | 1 | (2.8) | |
Radiation therapy | .03 | ||||||
Radiation | 57 | (28.8) | 32 | (19.8) | 25 | (69.4) | |
Mammosite | 12 | (6.1) | 12 | (7.4) | 0 | (0.0) | |
Chemotherapy | .83 | ||||||
Yes | 37 | (18.7) | 25 | (15.4) | 12 | (33.3) | |
No | 60 | (30.3) | 39 | (24.1) | 21 | (58.3) | |
Stage of breast cancer | .22 | ||||||
LCIS | 1 | (0.5) | 1 | (0.6) | 0 | (0.0) | |
I | 139 | (70.2) | 119 | (73.5) | 20 | (55.6) | |
IIa | 35 | (17.7) | 26 | (16.0) | 9 | (25.0) | |
IIb | 12 | (6.1) | 9 | (5.6) | 3 | (8.3) | |
IIIa | 11 | (5.6) | 7 | (4.3) | 4 | (11.1) | |
Tumor type | |||||||
DCIS | 79 | (39.9) | 71 | (43.8) | 8 | (22.2) | .02 |
LCIS | 7 | (3.5) | 5 | (3.1) | 2 | (5.6) | .61 |
Infiltrating ductal | 170 | (85.9) | 142 | (87.7) | 28 | (77.8) | .18 |
Tubular | 6 | (3.0) | 6 | (3.7) | 0 | (0.0) | .59 |
Mucinous | 2 | (1.0) | 2 | (1.2) | 0 | (0.0) | 1.00 |
Infiltrating lobular | 20 | (10.1) | 14 | (8.6) | 6 | (16.7) | .22 |
Combination | 1 | (0.5) | 1 | (0.6) | 0 | (0.0) | 1.00 |
Hormone replacement theory last 3 months | .36 | ||||||
Yes | 23 | (11.6) | 20 | (12.3) | 3 | (8.3) | |
No | 69 | (34.8) | 65 | (40.1) | 4 | (11.1) |
Note. AI = aromatase inhibitors; BDI = Beck Depression Inventory; POMS = Profile of Mood States; DCIS = ductal carcinoma in situ. Women may have more than one type of breast cancer tumor. Participants with DCIS also had another tumor to be eligible for the parent studies.
Occupations included higher executive/medium-sized business, teacher, health care professional.
Occupations included clerical and sales.
Occupations included skilled-manual, nonskilled manual, and unskilled.
Occupations included homemaker, disabled, student, retired, and no occupation.