Table 1.
Gene orthology of NF-E2-related factor 2 across the species.
| Species | Human Homo sapiens |
Cat Felis catus |
Chimpanzee Pan troglodytes |
Dog Canis lupus familiaris |
Cattle Bos taurus |
|
| |||||
| Official full name | nuclear factor (erythroid-derived 2)-like 2 | ||||
| Anthor name | nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2 | ||||
| Anthor name | HEBP1 | — | — | — | — |
| Gene synonyms | NFE2L2, NRF2 | NFE2L2, NRF2 | NFE2L2, NRF2 | NFE2L2, NRF2 | NFE2L2, NRF2 |
| Chromosome map | 2q31.2 | C1 | 2B | 36 | 2 |
| Genome sequence (NCBI Build) |
NC_000002.11 (GRCh37.p10) |
NC_108730.1 (Felis_catus-6.2) |
NC_006470.3 (Pan_troglodytes-2.1.4) |
NC_006618.3 (CanFam3.1) |
AC_000159.1 (Bos_taurus_UMD_3.1) |
| Primary source | HGNC: 7782 | — | — | — | BOS_1716 |
| Gene ID mapping (orientation*) |
4780
178095031−178129859 (−) |
101098812
165356974−165392728 (−) |
742622
181721941−181756837 (−) |
478813
20989206−21021893 (−) |
497024
19659540−19692048 |
| Ensemble gene ID (mapping) |
ENSG00000116044 (178092323−178257425) |
— | ENSPTRG00000012677 (181721949−181756285) |
ENSCAFG00000013506 (20987569−21022230) |
ENSBTAG00000019255 (19659540−19692048) |
| RefSeq ID, mRNA size |
NM_006164.4 (GI: 372620346), 2859 bp |
XM_003990893.1 (GI: 410968909), predicted, 2394 bp |
XM_001145876.2 (GI: 332814815), predicted, 2850 bp |
XM_535975.3 (GI: 345797173), predicted, 2570 bp |
NM_001011678.2 (GI: 147904941), 2409 bp |
| Protein ID (aa/MW§) |
NP_006155.2 (605/67696) |
XP_003990942.1 (606/67797) |
XP_001145876.2 (605/67686) |
XP_535975.1 (601/67087) |
NP_001011678.2 (607/67813) |
| UniProt ID | Q16236 | — | A2T6Y9 | — | Q5NUA6.2 |
| Variants# | 14 transcripts, 12 isoforms | 3 transcripts, 3 isoforms | 5 transcripts, 5 isoforms | 2 transcripts, 2 isoforms | — |
| Homology% gene/protein | 100/100 | 89.3/91.4 | 99.9/99.9 | 89.3/88.8 | 90.5/89.1 |
| Species | Rhesus monkey Macaca mulatta |
Chicken Gallus gallus |
Zebrafish Danio rerio |
Mouse Mus musculus |
Rat Rattus norvegicus |
|
| |||||
| Official full name | nuclear factor (erythroid-derived 2)-like 2 | nuclear factor, erythroid-derived 2, like 2 | |||
| Anthor name | nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2 | ||||
| Anthor name | HEBP1 | — | — | — | — |
| Gene synonyms | NFE2L2, NRF2, Mmu.966 | NFE2L2, NRF2 | nfe2l2, Nrf2, Nrf2a, wu:fc15g09, wu:fj67e03 | Nfe2l2, Nrf2, AI194320 | Nfe2l2, Nrf2 |
| Chromosome map | 12 | 7 | 9 | 2C3 (44.75 cM) |
3q23 |
| Genome sequence (NCBI Build) |
NC_007869.1 | NC_006094.3 |
NC_007120.5 (Zv9) |
NC_000068.7 (GRCm38.p1) |
NC_005102.3 (Rnor_5.0) |
| Primary Source | — | CGNC: 49604 | ZFIN: ZDB-GENE-030723-2 | MGI: 108420 | RGD: 620360 |
| Gene ID mapping (orientation*) |
707606
40848940−40884600 (−) |
396014
15304546−15320356 |
360149
1643746−1670288 |
18024
75675519−75704641 (−) |
83619
69041647−69069070 (−) |
| Ensemble gene ID (mapping) |
ENSMMUG00000001861 (40848948−40884174) |
ENSGALG00000009240 (16897956−16922637) |
ENSDARG00000042824 (1643631−1672715) |
ENSMUSG00000015839 (75675513−75704641) |
ENSRNOG00000001548 (58366693−58394118) |
| RefSeq ID, mRNA size |
NM_001257607.1 (GI: 383872375), 2335 bp |
NM_205117.1 (GI: 45384113), 2555 bp |
NM_182889.1 (GI: 33504557), 2149 bp |
NM_010902.3 (GI: 76573877), 2469 bp |
NM_031789.2 (GI: 402692377), 2305 bp |
| Protein ID (aa/MW§) |
NP_001244536.1 (606 /67703) |
NP_990448.1 (582/65160) |
NP_878309.1 (586/65757) |
NP_035032.1 (597/66770) |
NP_113977.1 (597/66825) |
| UniProt ID | F7GPD8 | Q90834 | Q8JIM1 | Q60795 | O54968 |
| Variants# | 2 transcripts, 2 isoforms | 1 transcript, 1 isoform | 1 transcript, 1 isoform | 1 transcript | 1 transcript, 1 isoform |
| Homology% gene/protein | 98.8/99.0 | 72.6/67.4 | 54.6/49.1 | 83.4/82.5 | 83.8/83.2 |
Refer to http://www.ncbi.nlm.nih.gov/homologene/2412 and reference [14] for cross-species homology. Details of homology scores and sequences can be also obtained by blast against human sequence (http://blast.ncbi.nlm.nih.gov).#Further information on transcript variants and protein isoforms are viewable by gene ID at NCBI (http://www.ncbi.nlm.nih.gov/refseq/rsg) and e!Ensemble (http://useast.ensembl.org/index.html) or by protein ID at UniProt (http://www.uniprot.org). §MW: predicted molecular weight from NCBI (MW in UniProt varies slightly.). RefSeq: reference sequence, aa: amino acids, and *gene in complement orientation.