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. 2013 Jul 7;2013:287697. doi: 10.1155/2013/287697

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Copyright © 2013 Ashraf A. Khalil et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of acute ischemia and reperfusion on in vivo BLS. (a) BLS was collected for 1 min in a nude mouse bearing bilateral U87-Luc subcutaneous thigh xenografts 5 min after injection of D-luciferin. The mouse was treated with a right thigh tourniquet proximal to the tumor. BLI was performed 2 min after tourniquet application and then 2 min after tourniquet removal. (b) BLS was collected at 1 min intervals for 60 min in nude mice bearing bilateral U87-Luc subcutaneous thigh xenografts. At 30 min, nicotinamide was administered via IP injection.