Table 2.

Binding Affinity Assay of the Compounds (1–6) for Human Opioid Receptors (subtype δ, κ and μ) and Cannabinoid Receptors (subtype CB₁ and CB₂)

	Opioid Receptors (%)			Cannabinoid Receptors (%)
Compound	δ	κ	μ	CB1	CB2
1	45.7	24. 7	8.7	n.t.a	n.t.
2	44.7	11.4	22.4	n.t.	44.5
3	−60.3	8.1	41.3	47.4	27.7
4	54.9	32.7	24.0	n.t.	46.3
5	−3.1	9.0	63.5	26.2	14.8
6	−27.8	−56.0	84.9	30.7	13.0
Naloxone	103.4	105.6	100.1	n.t.	n.t.
CP 55,940	n.t.	n.t.	n.t.	88.8	90.3

^aNot Tested