Table 1.
Rabbit response to acetylcholine and burst pacing—preimmune and postimmune studies
| Rabbit # | Acetylcholine | Preimmune | Postimmune | Anti-β2AR titer |
|---|---|---|---|---|
| 19 | 0 | N/R | N/R | 1:160,000 |
| 10 μM | N/R | NS/AT | ||
| 100 μM | N/R | NS/JT | ||
| 1 mM | N/R | NS/AT/AF | ||
| 20 | 0 | N/R | N/R | 1:1.28 million |
| 10 μM | N/R | N/R | ||
| 100 μM | N/R | sus AT | ||
| 1 mM | NS/AF | sus AF | ||
| 21 | 0 | N/R | N/R | 1:160,000 |
| 10 μM | N/R | N/R | ||
| 100 μM | N/R | N/R | ||
| 1 mM | N/R | sus AT | ||
| 22 | 0 | N/R | N/R | 1:1.28 million |
| 10 μM | N/R | N/R | ||
| 100 μM | N/R | sus AT | ||
| 1 mM | NS/AT | sus AT | ||
| 23 | 0 | N/R | N/R | 1:1.28 million |
| 10 μM | N/R | N/R | ||
| 100 μM | N/R | sus AT | ||
| 1 mM | NS/AT | NS/VPC |
AF = atrial fibrillation; AT = atrial tachycardia; β2AR = β2-adrenergic receptor; JT = junctional tachycardia; N/R = no response; NS = nonsustained; sus = sustained; VPC = ventricular premature contraction.