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. Author manuscript; available in PMC: 2014 Jun 4.
Published in final edited form as: Sci Signal. 2013 Jun 4;6(278):ra43. doi: 10.1126/scisignal.2003389

Fig. 2. Expression of miR-192 is increased in Ets-1–deficient MCs and MCs treated with Ets-1 siRNA.

Fig. 2

(A) Confirmation of Ets-1 absence in murine MCs from Ets-1–deficient (KO) mice compared with wild-type mice (WT) by Western blotting. (B) Basal or induced (TGF-β or control, CTR) miR-192 expression in Ets-1–deficient MCs compared to wild-type MCs. Data are means ± SEM from 3 experiments. *P < 0.05 by one-way ANOVA followed by Tukey’s post-hoc test analysis. (C) Col1a2 expression in Ets-1-deficient MCs compared twith wild-type MCs. Data are means ± SEM from 3 experiments. *P <0.05 by Student’s t-tests. (D and E) Abundance of Ets-1 mRNA (by PCR, D), and protein (by Western blotting, E) in MCs treated with Ets-1 siRNA compared to MCs treated with negative control oligonucleotides (NC). Data are means ± SEM from 3 experiments.*P <0.05; *** P <0.001 by Student’s t-tests. (F) Basal and TGF-β-induced miR-192 expression in MCs treated with Ets-1 siRNA. Data are means ± SEM from three experiments. *P < 0.05 by one-way ANOVA followed by Tukey’s post-hoc test analysis.