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High Throughput β-arrestin Screen Results
| PubChem CID |
Compound Number |
Agonist | Agonist Assay | Antagonist Assay | ||||
|---|---|---|---|---|---|---|---|---|
| GPR55 | GPR35 | CB1 | CB2 | GPR35 | CB1 | CB2 | ||
| EC50 (µM) | EC50 (µM) |
EC50 (µM) |
EC50 (µM) |
IC50 (µM) |
IC50 (µM) |
IC50 (µM) |
||
| 1792197 | 2 | 0.11/0.12 Avg 0.11 |
> 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
| 1172084 | 3 | 0.15/0.18 Avg 0.16 |
> 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
| 2440433 | 4 | 0.25/0.27 Avg 0.26 |
> 32 | > 32 | > 32 | > 32 | 21.8 | 15.1 |
| 1135734 | 5 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 | > 32 |
