Table 4.
Comparison of baseline characteristics of CKD cohort studies
| |
ROUTE |
CRIC [20],[21] |
CRISIS [22] |
MERENA [23] |
|---|---|---|---|---|
| |
Japan |
US |
UK |
Spain |
| n = 1138 | n = 3612 | n = 1325 | n = 1129 | |
| eGFR (ml/min per 1.73 m2) |
0 - 90 |
20 - 70 |
10 - 60 |
15 - 60 |
| Age (years) |
68 |
58.2 |
65.1 |
68 |
| Male gender (%) |
69.6 |
54 |
63.7 |
64 |
| BMI (kg/m2) |
23 |
32.1 |
|
28.4 |
| eGFR (ml/min per 1.73 m2) |
32.7 |
43.4 |
30.9 |
28 |
| Diabetes (%) |
37.1 |
47 |
32.4 |
40.8 |
| Hypertension (%) |
90.2 |
86 |
|
92.7 |
| SBP (mmHg) |
140 |
127.7 |
138.3 |
141 |
| DBP (mmHg) |
78 |
71.4 |
75.2 |
76 |
| ARB or ACEI (%) |
63 |
68 |
59.8 |
|
| Hb (g/dl) |
11.9 |
12.7 |
12.41 |
12.8 |
| LDL-C (mg/dl) |
110 |
102.5 |
|
116 |
| Ca (mg/dl) |
9.1 |
9.2 |
9.14 |
|
| P (mg/dl) |
3.6 |
3.7 |
3.72 |
3.7 |
| Intact PTH (pg/ml) |
109 |
53 |
93.2 |
145 |
| Prevalence of CVD (%) |
26.8 |
33.4 |
47.2 |
39.1 |
| Proteinuria (mean) |
2.16 g/gCr |
|
1.08 g/day |
1.2 g/day |
| Proteinuria (median) | 0.74 g/gCr | 0.17 g/day |
BMI body mass index, eGFR estimated glomerular filtration rate, SBP systolic blood pressure, DBP diastolic blood pressure, ARB angiotensin receptor blockers, ACEI angiotensin converting enzyme inhibitors, Hb hemoglobin, LDL-C low density lipoprotein cholesterol, Ca calcium, P phosphorus, PTH parathyroid hormone, CVD cardiovascular disease, g/gCr gram per gram creatinine.