Table 1.
Clinical data and average methylation levels at IGF2 and GNAS DMRs
| Normal pregnancy | Gestational hypertension | Preeclampsia | |||
|---|---|---|---|---|---|
| N |
81 |
23 |
56 |
|
|
| Maternal age (y) |
28.6±3.4 |
31.8±4.7 |
30.8±5.0 |
F=6.687 |
P=0.002 |
| Gestational age at delivery (w) |
38.70±1.37 |
38.29±1.90 |
34.07±3.29 |
F=72.509 |
P<0.001 |
| Birth weight (g) |
3288±395 |
3629±543 |
2473±818 |
F=45.591 |
P<0.001 |
| Fetal gender |
Male:41 |
Male:14 |
Male:30 |
X2=0.763 |
P=0.683 |
| Female:40 |
Female:9 |
Female: 26 |
|||
| Average methylation level at IGF2 DMR |
0.4609±0.0434 |
0.4526±0.0340 |
0.4425±0.0415 |
F=3.242 |
P=0.042 |
| Average methylation level at GNAS DMR | 0.5060±0.0559 | 0.5087±0.0523 | 0.5151±0.0530 | F=0.473 | P=0.624 |