Table 3.

Univariate and multivariate logistic regression analysis of socio-demographic and clinical factors associated with Mycobacterium tuberculosis genotype clustering among 832^a tuberculosis cases diagnosed in San Diego County, 2005–2008.

Variable	N	Univariate logistic regression			Multivariate logistic regression
		OR	95% CL	p	AOR	95% CL	p
Gender
Female	292	1.00			1.00
Male	540	1.66	1.24, 2.21	0.0006	1.63	1.20, 2.22	0.0020
Age (per 10 years)	832	0.90	0.84, 0.96	0.0025	0.86	0.80, 0.92	<0.0001
Race/ethnicity
White, non-Hispanic	76	1.00
Asian	311	1.22	0.74, 2.03	0.4396
Black	67	0.66	0.34, 1.27	0.2116
Hispanic	375	1.14	0.69, 1.87	0.6137
Country of birth
US-born	185	1.00
Foreign-born	646	0.68	0.49, 0.96	0.0270
Country of origin
U.S.	185	1.00			1.00
Mexico	258	0.70	0.47, 1.03	0.0671	0.78	0.52, 1.17	0.2270
Philippines	197	1.21	0.79, 1.85	0.3868	1.86	1.17, 2.95	0.0085
Vietnam	51	0.45	0.24, 0.83	0.0116	0.57	0.30, 1.09	0.0894
Other	141	0.36	0.23, 0.56	<0.0001	0.45	0.28, 0.71	0.0008
Injection drug use
No	811	1.00
Yes	21	1.48	0.59, 3.71	0.4020
Non-inject drug use
No	739	1.00
Yes	93	1.81	1.14, 2.89	0.0125
Excessive alcohol use
No	710	1.00
Yes	122	1.61	1.07, 2.41	0.0220
Homeless
No	772	1.00			1.00
Yes	53	3.83	1.84, 7.95	0.0003	3.44	1.65, 7.18	0.0010
Correction facility
No	756	1.00
Yes	76	2.19	1.29, 3.73	0.0037
Occupation health worker
No	808	1.00
Yes	24	1.03	0.45, 2.34	0.9487
Unemployed
No	407	1.00
Yes	425	0.73	0.55, 0.96	0.0232
HIV status
Negative	511	1.00
Positive	72	1.20	0.72, 2.01	0.4910
Unknown	249	0.60	0.44, 0.82	0.0012
Previous diagnosis of TB
No	779	1.00
Yes	49	1.28	0.70, 2.33	0.4197
Clinical site of disease
Pulmonary	571	1.00	0.31, 0.73	0.0007
Extrapulmonary	100	0.48	0.52, 1.06	0.0978
Both	161	0.74
Chest X-ray lesions
Normal	70	1.00
Cavitary lesions	163	2.34	1.32, 4.16	0.0037
Non-cavitary lesions	589	2.32	1.39, 3.85	0.0012
Treatment outcome
Completed treatment	668	1.00
Died	69	0.97	0.59, 1.61	0.9154
Days of treatment (per 10 days)	703	0.99	0.97, 1.00	0.0422

Genotypes were defined by spoligotype and mycobacterial interspersed repetitive units (MIRU) typing.

^aThe univariate logistic regressions included all study cases (N = 832); however, the final multiple regression model included only 825 cases due to cases with missing variable values that had to be excluded.