Figure 6. Immunoregulation in HTLV-1-infected patients with skin lesions of infectious or autoimmune nature.

The schematic representation illustrates the cytokines, chemokines and cell populations altered in the peripheral blood of patients chronically infected by HTLV-1 with infectious or autoimmune skin lesions. These immunological features give insight to the understanding of how the immune systemic biomarkers may be involved in the generation of protective and pathogenic responses and their potential association with proviral load and skin lesion.