Table 3. Phenotypic profile of innate immunity subsets.
Cell Phenotypes* | Clinical Groups | |||||
Control | HTLV-1+ | |||||
All | L(−) | L(+) | All | L(−) | L(+) | |
CD14+ CD16+/CD14+ | 8.5±2.2 | 8.8±2.7 | 8.1±1.6 | 12.3±5.7a | 11.3±5.0 | 12.8±6.1c |
CD14+CD16+HLADR++/CD14+CD16+ | 65.5±13.7 | 65.4±12.6 | 65.7±15.4 | 50.5±15.9a | 49.5±13.1b | 50.9±17.4c |
CD3−CD16−/+CD56−/+/CD3− | 10.7±4.1 | 11.5±4.6 | 10.0±3.8 | 18.2±8.3a | 18.6±6.0b | 18.1±19.2c |
CD3+CD16−/+CD56−/+/CD3+ | 0.5±0.3 | 0.6±0.2 | 0.4±2.1 | 0.9±0.7a | 0.6±0.2 | 1.0±0.2c |
CD4+CD25HIGH | 1.9±1.3 | 2.2±1.7 | 1.7±1.1 | 1.9±1.2 | 1.9±1.0 | 1.9±1.3 |
Monocyte subsets, NK-cells and NKT-cells and Regulatory T-cells in the peripheral blood of HTLV-1-infected patients and uninfected controls according to the absence (L(−)) or presence (L(+)) of dermatological Lesions.
Data are expressed as mean percentage (%) ± standard error of cell phenotype within a selected gated cell subset shown after the slash, except for CD3−CD16−/+CD56−/+ and CD4+CD25HIGH that were analyzed within gated lymphocytes.
Significant differences at P<0.05 are highlighted by letter “a”, “b” and “c” for difference between pairs of subgroups “All”, L(−) and L(+), respectively.