Figure 2. Rev-erb alpha regulates glucagon secretion in alphaTC1-9 cells.

(A) Rev-erb alpha gene expression and (B) protein expression from alphaTC1-9 cells treated for 24 hours with 50 nM control scramble siRNA (Sc) and 50 nM Rev-erb alpha siRNA(siRev) (n = 5). (C) Glucagon secretion after treatment with Sc and siRev in alphaTC1-9 cells (n = 5–6). *p<0.05, **p<0.01, *** p<0.001 versus Sc. Data are expressed as mean ±S.E.M.