Figure 1. Proportion of nuclei from 54 breast tumor touch preparations after FISH showing decreased copy number of BAC probe RP11-177H13 (8p21; black bars), and/or increased copy number of RP11-10G10 (8q22; gray bars).

Copy number changes are marked as loss or gain if at least 10% (marked by dashed lines) of nuclei show less than 2 signals from RP11-177H13 or more than 2 signals from RP11-10G10. Tumors are sorted into three graphs according to histological grade.