Table 1.
Meta-regression for HCV antibody prevalence in adult general population detainees and adult detainees with a history of injecting drug use
| General population detainees | Detainees with a history of IDU | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| N sources | Anti-HCV prevalence % (95% CI) | Meta-regression coefficient | Adj. R2 | p | N sources | Anti-HCV prevalence % (95% CI) | Meta-regression coefficient | Adj. R2 | p | |
|
| ||||||||||
| Retrospective cohort | 11 | 31 (22, 40) | 3 | 67 (43, 91) | ||||||
| Prospective cohort | 79 | 25 (22, 28) | −0·055 | 0·31% | 0·267 | 46 | 65 (59, 72) | −0·016 | −2·16% | 0·900 |
|
| ||||||||||
| Random sample | 11 | 18 (10, 26) | 4 | 67 (44, 90) | ||||||
| Convenience sample | 70 | 28 (24, 31) | 0·096 | 3·92% | 0·042 | 43 | 67 (61, 73) | −0·003 | −2·25% | 0·977 |
|
| ||||||||||
| Blood/sera | 69 | 24 (21, 27) | 37 | 65 (58, 72) | ||||||
| Saliva | 8 | 20 (14, 26) | 0·035 | −0·80% | 0·505 | 5 | 58 (38, 78) | 0·074 | −1·05% | 0·457 |
|
| ||||||||||
| Current only or mixed current/entrant | 35 | 24 (19, 29) | 14 | 63 (50, 76) | ||||||
| New entrants only | 23 | 30 (25, 34) | 0·047 | 1·03% | 0·206 | 16 | 76 (69, 82) | 0·126 | 8·12% | 0·073 |
|
| ||||||||||
| Mean/median age | 46 | - | 0·003 | −1·97% | 0·707 | 8 | - | 0·00003 | −17·01% | 0·999 |
|
| ||||||||||
| Percentage male | 79 | - | −0·0008 | 1·61% | 0·139 | 26 | - | 0·001 | −1·04% | 0·413 |
|
| ||||||||||
| Percentage with history of IDU | 50 | - | 0·005 | 49·23% | <·0001 | - | - | - | - | - |
|
| ||||||||||
| Year of data collection completion* | ||||||||||
| Pre-1995 | 16 | 38 (32, 45) | 7 | 77 (65, 88) | ||||||
| 1995–1999 | 23 | 25 (19, 31) | 13 | 68 (54, 82) | ||||||
| 2000–2004 | 21 | 27 (22, 32) | 15 | 65 (55, 75) | ||||||
| 2005–2012 | 33 | 20 (17, 23) | −0·009 | 12·57% | <·0001 | 16 | 55 (44, 66) | −0·139 | 12·67% | 0·007 |
N studies varies due to variable reporting in data sources. HCV, hepatitis C virus. IDU, injecting drug use.
*
Meta-regressions conducted using year of data collection completion as a continuous variable. Year categories based on five-year increments except for 2005–2012. Year category prevalence estimates and confidence intervals determined via stratified meta-analysis.