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. Author manuscript; available in PMC: 2014 May 21.
Published in final edited form as: J Sleep Res. 2013 Jun;22(3):264–271. doi: 10.1111/jsr.12009

Figure 3. Prolonged wakefulness increases cortical excitability.

Figure 3

(A) top: typical individual examples of evoked frontal LFPs during W0 and W4 (vertical red bars denote the timing of the stimuli). Middle, raster plots of corresponding MUA; bottom: total firing rates of the entire population (18 putative neurons) shown for 20 ms bins. Note a stronger increase in firing activity during the first 20 ms after the stimulus and a longer subsequent silence during W4 as compared to W0. (B) Mean values of the latency (in ms) to the first spike after electrical pulses. Values are mean + SEM (n=9 rats, 193 neurons). (C) The increase in neuronal firing rates in the first 20 ms after the electrical pulse relative to the mean firing rates in the 2 sec before the stimulus. Mean ratio ± SEM, n=9 rats, 193 neurons.