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. 2013 Jul 25;8(7):e70149. doi: 10.1371/journal.pone.0070149

Table 2. Frequency of different morphological defects in embryos at E8.5 from matings of Tbx20 +/- ; Tbx3 +/- double heterozygotes*.

Genotypes
Stage Morphology wt** Tbx20 -/- ; Tbx3 +/+ Tbx20 -/- ; Tbx3 +/- Tbx20+/+ ;Tbx3 -/- Tbx20 +/- ; Tbx3 -/- Tbx20 -/- ; Tbx3 -/-
E8.5 Normal 89 3*** 2*** 1*** 0 1***
Abnormal. looping 0 14 14 0 0 0
Abnormal looping / delay 0 3 3 0 0 3
Abnormal looping / dead 0 2 0 0 0 0
Delay 6 1 6 7 4## 3
Dead# 1 0 3 0 0 1
Total (n=167) 96 23 28 8 4 8
*

Double heterozygotes were either intercrossed or crossed to single heterozygotes.

**

wt, wild type; this group includes wild type and heterozygotes for one or both alleles.

***

Embryos were at the cardiac crescent stage, prior to heart looping.

#

Approximate time of death between E8.0 and E8.5; too degenerate to score for heart phenotype.

##

One of these embryos had a yolk sac defect.