Figure 3. Recognition of DBL2X and DBL3X peptides by plasma IgG from 100 pregnant women.
Seroprevalence is represented by bars as the % of responders. Peptides representative of signatures of high (HDS) and low (LDS) parasite density (Table 2 and Materials and Methods) and their optical density thresholds for seroprevalence (mean plus 3 standard deviations of OD in negative controls) were: HDS, S2A.1 = 0.690, S2B.1 = 0.210, S2C.1 = 0.266, S3A.1 = 0.293, S3B.1 = 0.140, S3C.1 = 0.295; LDS, S2A.2 = 0.450, S2B.4 = 0.266, S2C.3 = 0.480, S3A.3 = 0.366, S3B.2 = 0.151, S3C.3 = 0.195. P-values were calculated using McNemar's test (tests for S2A and S3A were not applicable due to low seroprevalence).