Table 2.
Characteristics of the Patients with Minimal Change Disease in relapse and remission (supernatants collected)
| Relapse | ||||||||
|---|---|---|---|---|---|---|---|---|
| Patient | Age (years) |
Weight (kg) |
Urinary Pr/Cr |
Serum Albumin (g/dl) |
Dose of Prednisone (mg) |
Frequency | Dose of Prednisone (mg/kg/d) |
CD80/GAPDH |
| 1 | 13 | 55 | 3.7 | 2.4 | 40 | qd** | 0.72 | 0.893 |
| 4 | 5 | 19.7 | 5.3 | 1.4 | 10 | qod* | 0.25 | 0.93 |
| 5 | 8 | 54.4 | 39.9 | 3.1 | 0 | 0 | 0 | 0.777 |
| 8 | 4 | 21 | 11.8 | 1.6 | 6 | qod | 0.14 | 0.955 |
| 12 | 5 | 21.4 | >300 mg/dl | 1.5 | 0 | 0 | 0 | 0.576 |
| 13 | 11 | 66.7 | 3 | 2.1 | 54 | qd | 0.8 | 0.938 |
| 14 | 4 | 17 | 21.5 | 1.8 | 30 | qd | 1.76 | 0.664 |
| 15 | 5 | 25.7 | 2.6 | 1.8 | 6 | qod | 0.11 | 1.678 |
| mean ± SD | 6.8 ± 3.4 | 35.1 ± 20 | 1.9 ± 0.6 | 18.2 ± 20.4 | 0.47 ± 0.6 | 0.9 ± 0.3 | ||
| Remission | ||||||||
| 2 | 17 | 48 | 0.04 | 4.7 | 0 | 0 | 0 | 0.513 |
| 3 | 8 | 36.9 | 0.07 | 4.6 | 54 | qd | 1.46 | 0.875 |
| 7 | 7 | 26.1 | 0.07 | 4.4 | 30 | qod | 0.57 | 0.471 |
| 8 | 4 | 17.5 | 0.1 | 3.6 | 6 | qod | 0.17 | 0.982 |
| 13 | 11 | 68.3 | 0.1 | 3.5 | 54 | qd | 0.79 | 0.865 |
| 15 | 5 | 23.8 | 0.2 | 4.3 | 6 | qod | 0.12 | 0.984 |
| 16 | 10 | 60 | 0.19 | 4.8 | 40 | qod | 0.33 | 0.626 |
| mean ± SD | 8.8 ± 4.3 | 40 ± 19.3 | 0.1 ± 0.1 | 4.3 ± 0.5 | 27.1 ± 23.2 | 0.49 ± 0.5 | 0.7 ± 0.2 | |
| Controls | ||||||||
| 17 | 13 | 50.8 | Negative | NA | 0 | 0 | 0.648 | |
| 18 | 13 | 54.9 | Negative | NA | 0 | 0 | 0.834 | |
| 19 | 19 | 74.6 | Negative | NA | 0 | 0 | 0.726 | |
| 20 | 12 | 39.8 | Negative | NA | 0 | 0 | 0.776 | |
| mean ± SD | 14.2 ±3.2 | 55 ± 14.5 | 0.7 ± 0.1 |
*
Every other day.
**
Every day