Table 2.
Independent associations of HLA supertypes and HLA alleles with HCV viremia among HCV seropositive women - shown are those HLA supertypes that retained significant or marginally significant (α < 0.10) false discovery rate (FDR)-adjusted q values after adjustment for multiple comparisons and those alleles not part of these supertypes that were significantly associated with HCV viremia in our prior study in this population1
| HLA supertype | PR (95% CI) | p value |
|---|---|---|
| DRB3 | 0.44 (0.25, 0.76) | 0.004 |
| DR8 | 1.76 (1.14, 2.72) | 0.01 |
| DR1*01 | 1.50 (0.90, 2.50) | 0.12 |
| A | 1.49 (0.97, 2.28) | 0.07 |
| Individual alleles | ||
| DRB1*07:01 | 1.73 (1.18, 2.53) | 0.005 |
| B*57:01 | 1.44 (0.70, 3.00) | 0.32 |
| B*57:03 | 1.89 (1.18, 3.02) | 0.008 |
| C*01:02 | 1.32 (0.72, 2.43) | 0.37 |
PR: Prevalence Ratio; 95% CI: 95% Confidence Interval
1
Results from a single multivariable log-binomial model with adjustment for race/ethnicity (non-Hispanic Black, non-Hispanic White, Hispanic)