Table 3. Case-control association results.
Marker | Allelesa | MAFb | Genotypes casesc | Genotypes controlsc | Pgenotypic value | Pallelic value | Ptrend value | ORdominant (95% CI)d; p-value | ORrecessive (95% CI)e; p-value |
rs521417 | a/C | 0.38 | 111/112/36 | 182/244/67 | 0.2287 | 0.2835 | 0.2808 | 0.780 (0.54 – 1.060); 0.1125 | 1.026 (0.664 – 1.588); 0.9067 |
rs4712827 | c/T | 0.46 | 78/118/63 | 143/247/103 | 0.4277 | 0.6679 | 0.6716 | 0.948 (0.682 – 1.318); 0.7509 | 1.217 (0.851 – 1.740); 0.2809 |
rs494723 | c/T | 0.29 | 151/93/15 | 249/206/38 | 0.1165 | 0.0437 | 0.0426 | 0.730 (0.539−0.989); 0.0418 | 0.736 (0.397 – 1.365); 0.3292 |
Results of the Polish case-control association analysis. aUppercase denotes the more frequent allele in the control samples, bMAF, minor allele frequency calculated from the control samples, cThe order of genotypes: DD/Dd/dd (d is the minor allele), dDominant model: dd + Dd vs DD (d is the minor allele), eRecessive model: dd vs Dd + DD (d is the minor allele).