Figure 1.

Experimental groups. Rats were treated with pilocarpine to induce status epilepticus, control rats received saline instead of pilocarpine. Bromodeoxyuridine (BrdU) was administered for 2 days, starting 9 days before perfusion. Spatial learning was evaluated by the latency to find a hidden platform in a water maze (WM). Production and survival of newborn cells in the subgranular zone of the granule cell layer were measured through counting of BrdU and doublecortin (DCX) labeled cells, 24 h after the last day of the WM task.