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Upper half depicting the pedigree chart of the family 150 and the hot water epilepsy (HWE) loci at 10q21.2-q22.3. Lower half reveals the pedigree chart of family 227. Key recombinant events in III: 4, III: 5 and IV: 3 are indicated by arrows. Seizure types and age at onset are indicated beside symbols; The HWE linkage is depicted in the chromosome 4q24-q28
