Table 5.

The system parameter values from the drug-independent model to describe the CVS

Parameter	Value	SE	CV	LLCI	ULCI	Value when Emax of amlodipine was fixed to 0.8 instead of 1
BSL_TPR (mmHg·mL−1·min−1)	2.32	0.132	5.69	2.06	2.58	2.32
BSL_MAP (mmHg)	147	1.38	0.939	144	150	147
kout_CO (1·h−1)	99 FIXED
kout_TPR (1·h−1)	0.260	0.129	49.6	0.00716	0.513	0.308
FB1 (1·mmHg−1)	0.00378	0.000148	3.92	0.00349	0.00407	0.00382
FB2 (1·mmHg−1)	0.00492	0.00101	20.5	0.00294	0.00690	0.00468

SE, SE of parameter estimate; CV, coefficient of variation; LLCI, lower limit of 95% CI; ULCI, upper limit of 95% CI.