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. Author manuscript; available in PMC: 2013 Jul 26.
Published in final edited form as: Gastroenterology. 2011 Jul 18;141(4):1323–1333. doi: 10.1053/j.gastro.2011.07.005

Figure 4.

Figure 4

Effect of anti-sense oligoribonucleotide (M-ASO) inhibition of miR-122a on TNF-α modulation of miR-122a, inulin flux, and occludin expression in Caco-2 monolayers. (a) M-ASO was transfected into filter-grown Caco-2 monolayer and the effect of M-ASO transfection on TNF-α induced increase in miR-122a expression was determined. (b) Effect of M-ASO transfection on TNF-α induced increase in inulin flux. (c) Effect of M-ASO transfection on TNF-α induced decrease in occludin mRNA expression. (d) Effect of M-ASO transfection on TNF-α induced decrease in occludin protein expression. * p < 0.01 vs control. ** p < 0.001 vs TNF-α treatment.