Figure - PMC

Skip to main content

View full-text article in PMC

. Author manuscript; available in PMC: 2013 Jul 26.

Published in final edited form as: Gastroenterology. 2011 Jul 18;141(4):1323–1333. doi: 10.1053/j.gastro.2011.07.005

The effect of miR-122a over-expression on mouse small intestinal permeability in-vivo. (a) Experimental design for pre-miR-122a transfection in-vivo. (b) Mouse small intestinal mucosal surface were transfected with pre-miR-122a in-vivo. Effect of pre-miR-122a transfection on mouse enterocyte miR-122a level in-vivo. Enterocytes were isolated from the mucosal surface by LCM. (c) Effect of pre-miR-122a transfection on mouse intestinal permeability in-vivo. (d) Effect of pre-miR-122a transfection on enterocyte occludin mRNA level. (e) Effect of pre-miR-122a transfection on intestinal tissue occludin protein level. * p < 0.01 vs control.

The effect of miR-122a over-expression on mouse small intestinal permeability in-vivo. (a) Experimental design for pre-miR-122a transfection in-vivo. (b) Mouse small intestinal mucosal surface were transfected with pre-miR-122a in-vivo. Effect of pre-miR-122a transfection on mouse enterocyte miR-122a level in-vivo. Enterocytes were isolated from the mucosal surface by LCM. (c) Effect of pre-miR-122a transfection on mouse intestinal permeability in-vivo. (d) Effect of pre-miR-122a transfection on enterocyte occludin mRNA level. (e) Effect of pre-miR-122a transfection on intestinal tissue occludin protein level. * p < 0.01 vs control.