Table 1.
Parameter | Study Population (n=243) |
Registry Patients without Echo (n=541) |
P |
---|---|---|---|
CLINICAL | |||
Age (year) | 60 ± 15 | 61 ± 14 | 0.86 |
Male gender | 63% (154) | 74% (398) | 0.004 |
Atherosclerosis Risk Factors | |||
Diabetes Mellitus | 35% (86) | 26% (142) | 0.009 |
Hypertension | 61% (149) | 59% (320) | 0.57 |
Tobacco Use | 24% (58) | 29% (156) | 0.15 |
Hypercholesterolemia | 39% (94) | 57% (306) | <0.0001 |
Prior Myocardial Infarction | 44% (108) | 50% (269) | 0.17 |
Coronary Revascularization | 28% (67) | 40% (268) | <0.0001 |
Percutaneous Intervention | 16% (39) | 31% (169) | <0.0001 |
Coronary Artery Bypass Grafting | 17% (42) | 27% (147) | 0.003 |
Ischemic Cardiomyopathy | 63% (154) | 74% (401) | 0.002 |
Atrial Fibrillation | 19% (45) | 14% (74) | 0.08 |
Lifetime History of Prior Cerebrovascular Event | |||
Cerebrovascular Accident (CVA) | 9% (22) | 7% (37) | 0.28 |
Transient Ischemic Attack (TIA) | 7% (16) | 4% (22) | 0.13 |
Therapeutic Regimen | |||
Aspirin | 58% (140) | 69% (371) | 0.003 |
Warfarin | 14% (35) | 19% (101) | 0.14 |
Thienopryidines | 6% (16) | 18% (98) | <0.0001 |
Beta-blocker | 51% (125) | 71% (386) | < 0.0001 |
ACE-Inhibitor | 46% (111) | 63% (343) | <0.0001 |
Angiotensin Receptor Blocker | 6% (15) | 13% (70) | 0.005 |
Loop diuretic | 31% (76) | 45% (244) | 0.0003 |
Spironolactone | 11% (26) | 18% (96) | 0.02 |
Digoxin | 16% (39) | 28% (150) | 0.0004 |
Nitroglycerin | 28% (150) | 18% (44) | 0.004 |
CARDIOVASCULAR MAGNETIC RESONANCE | |||
Left Ventricular Thrombus (DE-CMR) | 10% (24) | 6% (31) | 0.04 |
Left Ventricular Function and Morphology | |||
Ejection Fraction (%) | 28 ± 11 | 33 ± 10 | < 0.0001 |
Wall motion score | 1.7 ± 0.7 | 1.5 ± 0.7 | < 0.0001 |
% LV with akinesis or dyskinesis* | 24% (6 – 41) | 24% (6 – 35) | 0.054 |
End-diastolic volume (ml) | 210 ± 89 | 206 ± 85 | 0.50 |
End-systolic volume (ml) | 156 ± 83 | 142 ± 79 | 0.03 |
Aneurysm present | 16% (38) | 12% (63) | 0.12 |
Left Ventricular Infarction | |||
Myocardial Infarction (presence) | 71% (172) | 75% (404) | 0.25 |
Infarct size (% LV)* | 10% (0 – 25) | 16% (0 – 29) | 0.03 |
% LV with >50% transmural infarction* | 0% (0 – 24) | 12% (0 – 29) | 0.002 |
Numbers in boldface indicate P values < 0.05
Expressed as median (25th–75th percentile)