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Role of KV channels in coronary pressure-flow autoregulation. a Inhibition of coronary KV channels with 4AP significantly attenuated coronary blood flow at CPPs from 60 to 140 mmHg. 4AP administration did not affect the change in coronary blood flow at CPPs < 120 mmHg (b), the balance between coronary blood flow and MVO2 (c) or autoregulatory gain (d). Figures show grouped average traces for n = 7 swine. *P < 0.05 versus control, same CPP
