Partial sequence alignment of various bacterial CcPs. Gs: Geobacter sulfurreducens, Psa: Pseudomonas auruginosa, So: Shewanella oneidensis, Ne: Nitrosomonas europaea. Heme binding motifs (CXXCH) are marked with purple shading, and the three loop regions implicated in reductive activation are shaded in yellow, blue or orange.