Figure 4.
B+S microinjection within the preBötC and BötC did not result in apnea in vagus-intact rats (n = 7). A, Breathing frequency (f), duration of inspiration (TI), and duration of expiration (TE) measured under three different conditions: control/vagi intact (VI), after administration of B+S (VI-B+S), and after subsequent vagotomy (Vag). B, Diaphragm EMG activity and f during B+S injections. Top to bottom: Markers of injections; traces of integrated activity of the diaphragm (∫DIA), raw activity of the diaphragm (DIA), and f; markers of expanded traces. C, Expanded traces in control and after B+S injections.