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. Author manuscript; available in PMC: 2014 Jun 5.
Published in final edited form as: Clin Chim Acta. 2013 Feb 27;421:236–242. doi: 10.1016/j.cca.2013.02.021

Fig. 5.

Fig. 5

Intracellular Ca++ concentration in response to angiotensin II (10 nmol/l) stimulation was measured in cells obtained from a salt-resistant individual to validate the response in our experimental protocol. Intracellular Ca++ increased 1.78-fold (N = 3, *P < 0.05) over vehicle (VEH) in RPTCs. Losartan (AT1R antagonist, LOS, 10 μmol/l) alone showed no effect, but abrogated the angiotensin II effect (N = 3, **P < 0.01 vs angiotensin II alone) (ANOVA, Holm-Sidak test) demonstrating that a viable angiotensin type 1 receptor (AT1R) was present in these cells. The data are shown as mean ± SE of the mean.